Edward D'Antonio, PhD

Edward L. D'Antonio, PhD

Professor of Biochemistry and Structural Biology
Department of Natural Sciences

Bluffton campus
Science and Technology Building
Room 108
One University Boulevard
Bluffton, SC 29909
Office: 843-208-8101 Lab: 843-208-8167
Edward D'Antonio, PhD

Specialties: Structural Biology, Biochemistry, Chagas' Disease, Neglected Tropical Diseases, and Medicinal Chemistry. 

My group includes undergraduate researchers that utilize a variety of techniques ranging from analytical chemistry, biotechnology, enzymology, structural biology, and synthetic chemistry. I use structure-based drug design and screening approaches to develop new classes inhibitors for enzyme drug-targets found in parasites of trypanosomatid diseases.  These diseases include Chagas' disease (Trypanosoma cruzi), human African trypanosomiasis (Trypanosoma brucei), and leishmaniasis (Leishmania spp.).  Another goal of my research is to optimize existing inhibitor designs by increasing molecular interactions within the inhibitor's binding site. 

  • Education
  • Teaching
  • Research
BS in Chemistry, Millersville University (2003) - Advisor: Dr. Lyman H. Rickard

PhD in Chemistry, North Carolina State University (2010) - Advisor: Dr. Edmond F. Bowden

Postdoctoral Fellowship in Structural Biology, University of Pennsylvania (2010-2013) - Advisor: Dr. David W. Christianson

  • B295 Directed Studies in Biology
  • B399 Independent Study
  • B441 Principles of Biochemistry
  • B441L Principles of Biochemistry Lab
  • B451 Forensic Tech and Data Analysis
  • B111 General Chemistry I
  • B112 General Chemistry II
  • B450 Principles of Biochemistry
  • B450L Principles of Biochemistry Lab
  • Structural biology
  • Biochemistry
  • Chagas' Disease
  • Neglected tropical diseases
  • Medicinal chemistry